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Effect of leptin receptor function on viral replication.

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posted on 18.09.2014, 02:43 by Kathryn A. Radigan, Luisa Morales-Nebreda, Saul Soberanes, Trevor Nicholson, Recep Nigdelioglu, Takugo Cho, Monica Chi, Robert B. Hamanaka, Alexander V. Misharin, Harris Perlman, G. R. Scott Budinger, Gökhan M. Mutlu

Plaque forming units (pfu) were counted in MDCK cells treated with lung homogenates from db/db and C57BL/6 mice infected with influenza A virus (a) 1500 pfu/mouse on Day 4 and (b) 500 pfu/mouse on Day 2 and Day 4. We also measured (c) interferon-α (IFN- α) levels in BALF in wild-type and db/db mice 2 days after infection with influenza A virus (1500 pfu/mouse).