Effect of high fat diet on hyperinsulinemia in AT2KO mice.
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Plasma insulin levels in (A) male and (B) female WT and AT2KO fed on normal diet (ND) and high fat diet (HFD). Plasma insulin levels in different groups were determined using ELISA kit as per the manufacturer’s instructions. Data were analyzed using one-way ANOVA with Newman-keuls post hoc test and Student t test (p<0.05); n for males (WTND = 20; WTHFD = 8; AT2KOND = 6; AT2KOHFD = 6); n for females (WTND = 19; WTHFD = 20; AT2KOND = 16; AT2KOHFD = 16).