Effect of PDE6β1-313 on the inhibition of trypsin-activated PDE6 (tPDE6) by Pγ.
Figures are generally photos, graphs and static images that would be represented in traditional pdf publications.
The activity of tPDE6 was determined upon addition of increasing concentrations of Pγ in the absence (squares) or in the presence (circles) of 2 µM PDE6β1-313. The tPDE6 activity is plotted as a function of Pγ concentration. Results from one of three similar experiments are shown. The data were fit to sigmoidal dose-response equation using GraphPad Prizm Software. The calculated IC50 values (squares, 0.53±0.07 nM; circles, 1.6±0.2 nM) are significantly different (p<0.01).