Figure_5.tif (394.57 kB)
Effect of 10 µM CK-2066260 on tension-pCa curves at short (2.1 µm) and long SL (2.6 µm).
figureposted on 2013-02-21, 17:01 authored by Eun-Jeong Lee, Josine M. De Winter, Danielle Buck, Jeffrey R. Jasper, Fady I. Malik, Siegfried Labeit, Coen A. Ottenheijm, Henk Granzier
Result in WT in A and in NEB KO fibers in B. Increasing SL slightly shifts the curves left-ward (i.e., calcium sensitivity is increased) and CK results in an additional large shift. Results from six WT and six KO mice.