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ERdj4 deficiency enhances proliferation, survival and immunoglobulin isotype switching of LPS-treated B cells.

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posted on 15.09.2014 by Jill M. Fritz, Timothy E. Weaver

(A) CFSE dilution of B220+ cells treated with or without LPS. n = 3 samples/group. (B) Mean fluorescence intensity (MFI) of CFSE in B220+ cells treated with LPS. n = 3 samples/group. (C) Frequency of live B220+ cells treated with LPS. n = 3 samples/group. (D) Left panel, representative contour plots from flow cytometric analyses of B220+IgG3+ cells following treatment with LPS. Numbers indicate frequency of gated population for each genotype. Right panel, absolute numbers of B220+IgG3+ cells. n = 3 samples/group.

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