Figure_5.tif (1.77 MB)

Drug-gene interaction network.

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posted on 2013-04-23, 02:41 authored by Lun Yang, Elvin T. Price, Ching-Wei Chang, Yan Li, Ying Huang, Li-Wu Guo, Yongli Guo, Jim Kaput, Leming Shi, Baitang Ning

The figure indicates the relationship among the ten most influential DMETs and the top 100 prescribed medications. A line between a gene and a drug suggest that the DMET is involved in the metabolism or transporting of the drug. A drug is labeled as a circle and a gene is labeled.