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Differential tumour growth between WT and PTGER4 xenograft tumours is not due to enhanced angiogenesis.

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posted on 12.05.2011, 01:58 by Rob D. Catalano, Martin R. Wilson, Sheila C. Boddy, Andrew T. M. McKinlay, Kurt J. Sales, Henry N. Jabbour

(A) Detection of blood vessels in WT (n = 11 sections) and PTGER4 (n = 11 sections) xenograft tumours as determined by immuno-staining with the endothelial cell marker CD31. (B) Quantitative stereology of blood vessel density in WT and PTGER4 xenograft tumours as determined by percentage area positively stained for CD31. (C) mRNA expression of the angiogenic factor VEGF in WT (n = 10) and PTGER4 (n = 10) xenograft tumours.

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