Differential localization of viral antigen in spleens of primed and mock primed Cl13 infected mice.
Figures are generally photos, graphs and static images that would be represented in traditional pdf publications.
C57Bl6/J mice (n = 3/group) were primed, infected and spleens were harvested as in Fig. 4 at 72 hours post-infection. Spleens were flash frozen in OCT and 6–8 µm sections were prepared and stained with a guinea pig serum to LCMV GPC (green). Splenic microarchitecture was assessed by visualization of mellalophilic macrophages using anti mouse MOMA-1 antibodies (red). Sections from two mice/group are shown here and are representative of the group as a whole. Data are from one of two independent experiments.