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Diet effects on MiaPaCa-2 tumor burden and gene expression.

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posted on 07.05.2014, 03:38 by Alison E. Harvey, Laura M. Lashinger, Drew Hays, Lauren M. Harrison, Kimberly Lewis, Susan M. Fischer, Stephen D. Hursting

A, Mean body weight of athymic nude mice per group after 16 weeks of diet treatment (prior to tumor injection). B, MiaPaCa-2 tumor volume measured over 6 weeks of tumor growth. Line graphs represent mean ± SD. C, MiaPaCa-2 tumor weight measured at study termination; line in scatter plot represents median tumor weight. A, B, & C, n = 14/group. D, Diet effects on mRNA expression of NF-κB downstream targets. Data represent CR, relative to CON, mRNA expression, mean ± SEM (n = 6/group). Significance (p<0.05) is denoted by *. CON, control; CR, calorie restriction.

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