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Detailed analysis of the commonly deleted region at 7q22.1 by use of two different CGH arrays.

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posted on 20.02.2013, 14:34 by Cristina Robledo, Juan L. García, Rocío Benito, Teresa Flores, Manuela Mollejo, José Ángel Martínez-Climent, Eva García, Norma C. Gutiérrez, Miguel A. Piris, Jesús M. Hernández

Three cases showed loss in the region (43SMZL, 06SMZL and 14SMZL) between 99925039–101348479 bp (size 1.5 Mb), while the CGH array did not reveal any abnormality of the 7q22.1 region in the control SMZL (18SMZL). (Red, losses; green, gains; yellow, normal; blue, non-informative oligonucleotide hybridization). Figure 3C shows a close-up of a selected region, illustrating the loss on 7q22.1 in three SMZL patients.

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