Dectin-1 stimulated DCs prime CD4 T cells to induce IgG and IgA in B cells.

Naïve T cells primed by DCs as in figure 2 were cultured with allogeniec, purified B cells for two weeks. IgG and IgA secretion was determined by ELISA. A. Bar graph depicts the level of IgG in the supernatant. B. Bar graph depicts the level of IgA in the supernatant. Figure is mean ± S.E. of 4 such experiments. * Significant (<0.05), ** highly significant (<0.005).C. Bar graphs depict the level of IgG in the supernatant after culture of B cells with DC-T cell supernatant. D. Bar graphs depict the level of IgA in the supernatant after culture of B cells with DC-T cell supernatant.