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Decreased cell proliferation is detected in intestines of klf4a-overexpressed embryos.

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posted on 2011-06-08, 02:38 authored by I-Chen Li, Chein-Tso Chan, Yu-Fen Lu, Yi-Ting Wu, Yi-Chung Chen, Guo-Bin Li, Che-Yi Lin, Sheng-Ping L. Hwang

(A) Images of p-Histone H3-stained cells in intestines of 72-hpf lacZ- and klf4a-overexpressed embryos are shown. Comparison of p-Histone H3-stained cell percentages in intestines of lacZ- and klf4a-overexpressed embryos is shown. Arrows indicate p-Histone H3-stained cells. Error bars indicate the standard error. Student's t-test was conducted to compare klf4a- with lacZ-overexpressed embryos. (B) Images of BrdU-labeled cells in the foregut, midgut, and hindgut of 72-hpf lacZ- and klf4a-overexpressed embryos are shown. Comparison of BrdU-labeled cell percentages in intestines and in respective foregut, midgut, and hindgut of lacZ- and klf4a-overexpressed embryos are shown in panel A. Arrows indicate BrdU-labeled cells. Error bars indicate the standard error. Student's t-test was conducted to compare klf4a- with lacZ-overexpressed embryos.

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