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Cytocochleogram of wild-type and mutant Nox3 mice (8A).

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posted on 16.04.2015 by Joel Lavinsky, Amanda L. Crow, Calvin Pan, Juemei Wang, Ksenia A. Aaron, Maria K. Ho, Qingzhong Li, Pehzman Salehide, Anthony Myint, Maya Monges-Hernadez, Eleazar Eskin, Hooman Allayee, Aldons J. Lusis, Rick A. Friedman

No significant difference in OHC counts were detected among wild-type, Nox3het/+ and Nox3het/Nox3het. OHC preparations of immunostained (40x) post-noise exposure cochleae (8B) at the 8 kHz tonotopic location (red, rabbit anti-myosin6) demonstrate a small impact with the loss of apical OHC (2 weeks post-noise exposure). Homozygous = Nox3het/Nox3het: Heterozygous = Nox3het/+: Wild-type = C57BL/6JEiJ strain.