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Correspondence between calculated ΔGs for Arg at the −2 and −5 subsites and their SCSs.

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posted on 17.11.2011, 00:22 by Avraham Ben-Shimon, Masha Y. Niv

Kinases for which the SCS contains (or does not contain) Arg at the investigated substrate positions are colored orange (gray). Mixed coloring represents the exceptional case of PKB which uses P−5 Arg to bind at the −2 subsite. (A,B) The calculated ΔG values of Arg at the −5 and −2 subsites, respectively.