Correlation of FAIRE LogR Ratio with FAIRE-seq Peaks.
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posted on 2012-08-16, 00:27 authored by Andrew J. P. Smith, Philip Howard, Sonia Shah, Per Eriksson, Stefan Stender, Claudia Giambartolomei, Lasse Folkersen, Anne Tybjærg-Hansen, Meena Kumari, Jutta Palmen, Aroon D. Hingorani, Philippa J. Talmud, Steve E. HumphriesThe graph shows the correlation of FAIRE-enriched SNP intensity using Illumina CVD BeadChip with FAIRE-seq peak intensity from the GM12878 lymphoblast cell line. The (mean log R ratio from three FAIRE-enriched DNAs) – (mean log R ratio from their respective control DNAs) were compared with known FAIRE-seq intensities (0 = no FAIRE-seq enrichment; 1–200 = lowest level of FAIRE-seq enrichment; 800–1000 = highest FAIRE-seq enrichment). There is a strong correlation between SNP intensity and FAIRE-seq peak intensity (p = 2.34×10−82).
