Copolymer-mediated induction of CCL22 and CXCL13 in MHC Class II KO mice.

Female MHC Class II deficient mice and their littermate controls (n = 9–10) were administered one subcutaneous dose of 50 mg/kg YFAK, 50 mg/kg YEAK, or Vehicle Control. Blood was collected and plasma was prepared 30 minutes post administration and tested for CCL22 (A) and CXCL13 (B). Data is shown as mean (pg/mL) ± SEM. Significance was calculated using an unpaired t-test: YFAK or YEAK vs. Vehicle Control + p≤0.05; + + p≤0.01; + + + p≤0.001; + + + + p≤0.0001; YFAK vs. YEAK * p≤0.05; ** p≤0.01.