Contractility of isolated cardiac myocytes from wild type (WT) and TGF-β1 transgenic (TGF-β1) mice.
(A) Representative original registrations of cell shortening (dL/L) under basal conditions and upon isoprenaline stimulation (10 µM). (B) Contractile response of isolated cardiomyocytes from WT and TGF-β1 mice to increasing concentrations of isoprenaline (n = 100 in each group). (C) Contractile response of isolated cardiomyocytes to 10 µM isoprenaline in the various treatment groups (n = 97–135 in each group). *p<0.05 vs. WT.