Comparison of the PV94 and P2 replication proteins and origins of replication.
(A) Conserved motifs (A, B and C) of the replication proteins. The two tyrosine residues within motif C which are part of the active site of P2 protein A are marked by an asterisk. (B) Alignment of the P2 origin of replication located within gene A with the corresponding region of PV94 ORF14. Arrows indicate the cleavage site at the replication origin.