Comparison of samples from normal and IPF, normal and sarcoidosis, and IPF and sarcoidosis.
Unsupervised TWC results for each comparison without outlier samples. (A) Unsupervised hierarchical clustering of samples of IPF (n = 38) and normal (n = 20) with 2,946 IPF up regulated and 466 IPF down regulated genes. (B) Unsupervised hierarchical clustering of samples of sarcoidosis (n = 16) and normal (n = 17) with 920 sarcoidosis up regulated and 176 sarcoidosis down regulated genes. (C) Unsupervised hierarchical clustering of samples of IPF (n = 16) and sarcoidosis (n = 12) with 2,051 IPF up regulated genes and 961 IPF down regulated IPF genes. Colorbar in the upper right corner shows the relative quantity of each gene, from light green to bright red corresponds to relatively lower to higher expressions. Abbreviations: Normal = normal lung tissue samples, IPF = idiopathic pulmonary fibrosis lung tissue samples, Sar = sarcoidosis lung tissue samples. Samples numbers correspond to those labeled in Table S2.