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Comparison of inflammatory cytokine mRNA levels between different wound types.

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posted on 2013-02-20, 01:10 authored by Akhil K. Seth, Matthew R. Geringer, Seok J. Hong, Kai P. Leung, Robert D. Galiano, Thomas A. Mustoe

Polybacterial wounds containing S. aureus mutant (MT) revealed a significantly decreased level of IL-1β (A) and TNF-α (B) expression relative to polybacterial wild-type (WT) wounds containing UAMS-1 and PAO1. The expression level S. aureus MT-containing polybacterial wounds were of similar magnitude to single-species WT wounds. (*p<0.05, **p<0.01, ***p<0.001) (n = 8–10 wounds/group).