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Comparison of 68Ga-DOTATATE and 18F-FET in GBM.

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posted on 2015-03-25, 04:15 authored by Constantin Lapa, Thomas Linsenmann, Katharina Lückerath, Samuel Samnick, Ken Herrmann, Carolin Stoffer, Ralf-Ingo Ernestus, Andreas K. Buck, Mario Löhr, Camelia-Maria Monoranu

A single patient (#15) underwent both SSTR- as well as amino acid-based PET. Both modalities show highly comparable tracer uptake.

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Tumor-Associated Macrophages in Glioblastoma Multiforme—A Suitable Target for Somatostatin Receptor-Based Imaging and Therapy?
PLOS ONEPLOS ONE

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tamtracerSSTR 2A expressionresident microgliaSSTR 2A immunostainingPositron emission tomographyresident microglial cellsGBM.Methods 15 samplestumor cellsSomatostatin receptor imagingDOTATATEglioma cellssomatostatin receptor 2cell surfacemacrophageimmunohistochemical staining patterns.ConclusionSSTR 2A

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