Clinicopathological significances of pre-operative plasma OPN level.

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posted on 2015-05-11, 03:10 authored by Lui Ng, Timothy Ming-Hun Wan, Colin Siu-Chi Lam, Ariel Ka-Man Chow, Sunny Kit-Man Wong, Johnny Hon-Wai Man, Hung-Sing Li, Nathan Shiu-Man Cheng, Ryan Chung-Hei Pak, Alvin Ho-Kwan Cheung, Thomas Chung-Cheung Yau, Oswens Siu-Hung Lo, Dominic Chi-Chung Foo, Jensen Tung-Chung Poon, Ronnie Tung-Ping Poon, Roberta Wen-Chi Pang, Wai-Lun Law

(A) Correlation of pre-operative plasma OPN level with the paired tumor OPN transcript level in 32 CRC patients (R = 0.452, p = 0.010; Pearson correlation). (B) Correlation of pre-operative plasma OPN level with tumor size (R = 0.390, p<0.001; Pearson correlation). (C) Comparison of pre-operative plasma OPN levels in patients with tumor ≥5 or <5 (p = 0.003; Student’s t-test) (left). (D) Comparison of pre-operative plasma OPN levels in patients with lower (I to II) or higher stage (III to IV) (p<0.001; Student’s t-test). (E) Comparison of pre-operative plasma OPN levels in patients with or without distant metastasis (p = 0.003; Student’s t-test). (F) Comparison of pre-operative plasma OPN levels in patients with or without post-operative metastasis (p = 0.951; Student’s t-test). All data are representative of three independent experiments.