Changes in the immunological index after Salacia reticulata extract (SRE) ingestion.

(a) Changes in the T-cell proliferation index from the initial values to the values after 4 weeks are shown in the plot. Although the index decreased by 0.05 ± 0.10 in the P group, it increased by 0.24 ± 0.08 in the SRE group (p < 0.05 for intergroup comparison). The values represent the mean ± standard deviation. (b) Changes in the CD4⁺ naïve T-cell count from the initial values to the values after 4 weeks are shown in the plot. The cell count increased by 19.67 ± 14.26/μl in the P group, whereas it increased by 56.80 ± 12.50/μl in the SRE group (p < 0.0602 for intergroup comparison). (c) Changes in the immunological age from the initial values to the values after 4 weeks are shown in the plot. The age increased by 0.80 ± 0.99 years in the P group, whereas it decreased by 2.00 ± 0.81 years in the SRE group (p < 0.05 for intergroup comparison). *p < 0.05.