Figure_4.tif (754.04 kB)
Change of xenograft size in each mouse over the 4-weeks of treatment period in the untreated (A), nilotinib (B) and imatinib (C) groups.
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posted on 2014-10-23, 03:18 authored by Jiang Wei, Marcus Freytag, Yvonne Schober, Wolfgang A. Nockher, Victor F. Mautner, Reinhard E. Friedrich, Paul W. Manley, Lan Kluwe, Andreas KurtzGroup-means (D) differed significantly among the three groups (P<0.05).
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Plexiform Neurofibromamouse spleen cellsbody weight increasesciatic nerve7 micenilotinibddrimatinibnerve sheath tumorsresolution ultrasound measurementgraft sizesstdneurofibromatosis type 1.Vivo Plexiform neurofibromaspdgfrtyrosine kinase inhibitorKIT receptor kinasesprototype imatinibxenografted tumor fragmentspnf