CD4+ T cells expressing LIR-1 following treatment with benznidazole in subjects with increased CD4+LIR-1+ T cells at baseline.
figure
posted on 2012-05-04, 00:46 authored by Rafael J. Argüello, María C. Albareda, María G. Alvarez, Graciela Bertocchi, Alejandro H. Armenti, Carlos Vigliano, Patricia C. Meckert, Rick L. Tarleton, Susana A. LaucellaPBMCs from T. cruzi-infected subjects were taken prior and at different time points following treatment with benznidazole and stained with anti-CD4 and anti-LIR-1 monoclonal antibodies. Plots show representative data for single subjects from 10 chronically infected subjects. Significant changes in the levels of CD4+LIR-1+ T cells, as defined in Materials and Methods are depicted with dotted lines. Horizontal line, cut-off CD4+LIR-1+ T cell levels in the normal range, as defined in Material and Methods.
