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Binding modes of a Gsp homologue.

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posted on 26.02.2013, 12:09 by Oliver Koch, Daniel Cappel, Monika Nocker, Timo Jäger, Leopold Flohé, Christoph A. Sotriffer, Paul M. Selzer

Two major conformations of the spermidine moiety of the Gsp analogue (C) are observed. In the binding mode A loss of hydrogen bonds (orange dotted lines.) to Glu407 suggests weaker binding than in binding mode B.

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