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BCG-pAg85A combination induces Ag85A-specific IgG antibodies.

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posted on 2015-07-14, 03:40 authored by Nicolas Bruffaerts, Lasse E. Pedersen, Gaëlle Vandermeulen, Véronique Préat, Norbert Stockhofe-Zurwieden, Kris Huygen, Marta Romano

A. Ag85A-specific antibodies as detected at day -1 before BCG priming and at days 20, 41, 63 and 118 of the vaccination protocol. Mean O.D. values (490/620nm) of individual sera diluted 1:200 are shown for group 1 (black symbols), group 2 (blue symbols) and group 3 (green symbols). B. IgG1:IgG2 ratio of Ag85A specific antibodies measured at day 63 of vaccination on sera diluted 1:50.

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Increased B and T Cell Responses in M. bovis Bacille Calmette-Guérin Vaccinated Pigs Co-Immunized with Plasmid DNA Encoding a Prototype Tuberculosis Antigen
PLOS ONEPLOS ONE

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vaccinatedTh 1 helper typealternative animal modelcombinationifnAg 85Atuberculosis vaccineT cell responsesintracellular cytokine stainingprototype TB antigenT lymphocyte responsesbcgslaPrototype Tuberculosis Antigenplasmid DNA encodingppdil

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