Apparently altered methylation patterns in certain genes.

The picture shows six Signalmap snapshots of the microarray signals (green) from apparently differentially methylated genes after the particular radiation treatments and recovery times. Above the treatment description are the CpG islands (black). The signals framed by the red and blue rectangles are significantly (*) different methylated pairs of a control and a treatment, as determined by bioinformatics analysis. A. Signalmap snapshots of the genes MBP (0 days, 4 Gray vs. 7 days, 4 Gray (red rectangles) and 7 days, 0 Gray vs. 7 days, 0.1 Gray (blue rectangles), CLEC18C (0 days, 4 Gray vs. 7 days, 4 Gray (red rectangles) and a Y chromosomal region (7 days, 0 Gray vs. 7 days, 0.1 Gray (red rectangles) of HBEC. B. Signalmap snapshots of the genes CLEC18A (7 days, 0 Gray vs. 7 days, 1 Gray, red rectangles), SDHALP1 (7 days, 0 Gray vs. 7 days, 4 Gray, red rectangles) and ZCCHC16 (7 days, 0 Gray vs. 7 days 1 Gray, red rectangles) of HFB cells.