Analysis of 3-D Structure of SIV

(A) Segmented representation of the surface and interior of a single virus from the data shown in Figure 1. For the sake of clarity, only selected regions of the interior and exterior are highlighted: elements shown include the viral envelope (magenta), viral spikes (red), core (yellow), and interior (translucent purple).

(B) Surface plot showing automated detection of spikes on the surface of the viral membrane.

(C) Nearest neighbor analysis to measure the distribution of distances between neighboring spikes.