Amino acid sequence alignment of TRIM5α orthologues examined in this study.
Consensus amino acid sequences of TRIM5α. as well as TRIM5αhu (Hu), TRIM5αrh (Rh), TRIM5αag (Ag) and TRIM5αcy (Cy) amino acid sequences are shown. Identical residues are indicated by dots. Gaps are indicated by dashes. HindIII site in the coiled-coil domain was used as the junction for the chimeras used in this study.