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Activity profile of 102 compounds active in CLL primary patient cells compared to normal donor lymphocytes and selected cell lines.

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posted on 2013-09-20, 02:11 authored by Min Shen, Yaqin Zhang, Nakhle Saba, Christopher P. Austin, Adrian Wiestner, Douglas S. Auld

Drug names are given at right and the cell types are listed at the bottom of the heat map. Active means compounds in curve class 1.1, 1.2, 2.1 and 2.2 curves with efficacy higher than 60%; Inactive means compounds with class 4 curves; Inconclusive designates all other compounds including those shallow curves and curves with single point extrapolated activity.