Activation results during learning (Day 1).

A: JULIDE results. At Day 1, the hippocampus (HP) and the parietal associative cortex (PTLp) are the most activated regions during learning, whereas after the task they are no longer activated. t-test comparison between Day 1 trained mice and Active Control (AC). Uncorrected p-value  = 0.02. Clusters circled in red show significant activation after FWE and FDR corrections (corrected p-values <0.01). B: MCID results for the parietal associative cortex (PTLp). Increase in glucose consumption, measured as 2DG uptake, in the parietal cortex (PTL) the first (Day 1) day of training. t-test comparison between Day 1 trained mice (n = 7) and Active Control (AC; n = 8). *p-value <0.01.