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Ablating adult neurogenesis does not affect fear conditioning.

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posted on 2013-09-05, 02:10 authored by James O. Groves, Isla Leslie, Guo-Jen Huang, Stephen B. McHugh, Amy Taylor, Richard Mott, Marcus Munafò, David M. Bannerman, Jonathan Flint

A Freezing behavior of GCV-treated wild type (n = 7) and GFAP-TK (n = 10) rats during 60 s preceding a tone previously paired with a shock (Pre Tone) and during the first 20 s of tone presentation (Tone). Data represent % time spent freezing during each time period (± sem). B Freezing behavior of GCV-treated wild type (n = 7) and GFAP-TK (n = 10) rats in a context previously associated with shock presentation. Data represent % time freezing during 4 minutes (60 s time bins; ± sem). *p<0.05 tone significantly different from pre-tone. Wild type data are represented by an open circle connected by an interrupted line, GFAP-TK data are represented by filled squares and a solid line.

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