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A discrete view of the frequency multiplier behaviour.

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posted on 17.02.2011, 02:12 by Oliver Purcell, Mario di Bernardo, Claire S. Grierson, Nigel J. Savery

The dynamics can be split into four stages, starting at stage 1 and cycling round clockwise. As the level of input switches on and off twice, each of the repressors has only made one oscillation. The network therefore functions as a frequency multiplier of one half. See main text for an explanation of the network state at each stage.