A bioinformatics approach revealed three conserved motifs in Clr2.
(A) Sequence alignment between Clr2 and 11 other similar fungal proteins. Three conserved motifs, named C2SM1-3, always present in the same order were identified. C2SM1 (red) and C2SM2 (light blue) are present in the N-terminal part of Clr2 and C2SM3 (dark blue) in the C-terminal part. Height of the boxes reflects significance (p-value). Logos for the three motifs that highlight conserved residues (B) C2SM1 (C) C2SM2 (D) C2SM3