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ATV concentrations in plasma, lymph nodes, liver and spleen.

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posted on 05.01.2016 by Andrea L. Martinez-Skinner, Mariluz A. Araínga, Pavan Puligujja, Diana L. Palandri, Hannah M. Baldridge, Benson J. Edagwa, JoEllyn M. McMillan, R. Lee Mosley, Howard E. Gendelman

Following intraperitoneal injection of nanoATV, plasma, mesenteric lymph nodes, liver and spleen were collected 1, 4, 12, 24, 48, and 72 h post injection. ATV concentrations were determined by UPLC-MS/MS. Tissue drug levels are reported as mean ± SEM for 4–8 mice/time point.