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1-D-MT does not inhibit the proliferation or cell cycle progression of SKOV-3 cells.

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posted on 20.02.2013, 18:13 by Christiane A. Opitz, Ulrike M. Litzenburger, Uta Opitz, Felix Sahm, Katharina Ochs, Christian Lutz, Wolfgang Wick, Michael Platten

(A) 3[H] methylthymidine incorporation of SKOV-3 cells treated with 1 mM 1-D-MT (black bar) or vehicle (white bar) for 6 days. (B) Cell cycle analysis of SKOV-3 cells treated with 1 mM 1-D-MT or vehicle for 48 h. (C) Proliferation analysis of CFSE-stained lymphocytes from 6 day cocultures of MLR with 2000 SKOV-3 cells, treated with indicated concentrations of 1-D-MT (upper panel). Plot of the cell numbers in each generation of the above experiment (lower panel).