1,25(OH)2D3 treatment significantly protected mice from development of EAE.
figure
posted on 2013-03-15, 13:45 authored by Bo Li, David J. Baylink, Chandra Deb, Claudia Zannetti, Fatima Rajaallah, Weirong Xing, Michael H. Walter, K.-H. William Lau, Xuezhong QinEAE was induced by immunonization with MOG (Material & Methods). Mice were injected i.p. with 2 µg of 1,25(OH)2D3 one day before MOG injection and then 0.1 µg 1,25(OH)2D3 every other day till day 14 post-MOG injection. Body weight (A) and clinical score (B) were determined at day 14 post-MOG injection. Data represent the means ± SEM (n = 7) from two independent experiments. *** P<0.001.
