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11a induces G1/S phase cell cycle arrest in a dose dependent manner in HCT116 isogenic cell lines.

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posted on 16.09.2013, 02:02 by Zibo Zhao, Lu Wang, Zhi Wen, Serife Ayaz-guner, Yidan Wang, Paul Ahlquist, Wei Xu

(A) Western blot against p53, Cyclin D1, p21 and Hsp90 as the loading control. (B) Histograms of the DNA FACS analysis of the cultures from panel A. (C) Quantification of the FACS analysis and cell cycle distribution of the two cell lines treated with 0, 5, 10, 50, or 100 nM 11a in 0.1% DMSO for 12 hours.