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ω-3 fatty acid lipidomic profiles of steatotic and non-steatotic livers during perfusion.

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posted on 24.01.2020, 18:48 authored by Siavash Raigani, Negin Karimian, Viola Huang, Anna M. Zhang, Irene Beijert, Sharon Geerts, Sonal Nagpal, Ehab O. A. Hafiz, Fermin M. Fontan, Mohamed M. Aburawi, Paria Mahboub, James F. Markmann, Robert J. Porte, Korkut Uygun, Martin Yarmush, Heidi Yeh

Ratio of metabolite concentration fold change at each hour of perfusion compared to pre-perfusion concentration shown for the free fatty acid (FFA) form of (a) eicosapentaenoic acid (EPA), (b) docosapentaenoic acid (DPA), and (c) docosahexaenoic acid (DHA). (d) Heatmap of EPA, DPA, and DHA concentration fold changes in cholesterol ester (CE), FFA, monoacylglycerol (MAG), diacylglycerol (DAG), and triacylglycerol (TAG) forms. ** indicates P≤0.05, * indicates 0.05