YH250 sustains LT—HSC in vitro.
figureposted on 09.05.2017, 17:38 by Yi Zhao, Kaijin Wu, Cu Nguyen, Goar Smbatyan, Elisabeth Melendez, Yusuke Higuchi, Yibu Chen, Michael Kahn
(A) LSK34-135-150+ 48- cell preparation is depicted. (B) Cell surface marker changes from DMSO or YH250 treated animals in in vitro culture. Results are summary of 3 independent experiments.
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FDAnon-differentiative proliferationYH 250 24 hours post irradiationagentSmallsublethallyadministrationmechanismstimulationsurvivalmoleculeARS mitigation post radiation exposureHSC populationinteractionhematopoiesiantagonisthematopoietic recoveryHSC proliferationlethallyblood count recoveryantagonize