Wild type yeast cells display lifespan variation.

(A) 917 diploid wild type BY4743 cells were aged on YPD plates and their lifespans were recorded. (B) End-of-life cell aging pictures were analyzed for budded (208 cells) or unbudded (508 cells) status. The lifespan curves of budded and unbudded cells are shown. (C) Lifespan values of the 917 cells were binned every 5 generations into a histogram, with a normal curve superimposed on the data to illustrate the relatively normal distribution. (*** = p<0.0001).