Volcano plots showing differentially expressed miRNAs in serum and macrophages of infected jirds.
Scatter plot of L. sigmodontis-derived miRNAs (orange dots, orange boxes) and murine-derived miRNAs (blue dots, black boxes) that are differentially expressed (DE) in naïve and infected serum (A) and macrophages (B) from jirds. Horizontal lines represent the cut-off for determining significant DE miRNAs in these datasets (p < 0.05). C) Principal Component Analysis of the DESeq2 analysis of naïve vs. infected jirds serum and macrophages. The samples are color-coded and the legend on the right indicates the corresponding experimental groups.