Variation in OS biomarkers by year before individuals’ death.
*A) 8-OHdG decreased and B) Isoprostanes increased among the 4 subjects as they approach death. D) Neopterin increased among past-prime individuals as they approached death. Solid line drawn with simple linear regression, unlike mixed effect models that determined significance. Black dotted line represents population median in biomarker from samples unrelated to epidemic, injury or eventual death.