VZV infected NK cells produce less IFN-γ and TNF upon PMA/I stimulation.
PBMCs were mock cultured, exposed to VZV, or VZV infected for 2 days (A) or 1 day (B) and stimulated with PMA/I for flow cytometry analysis of IFN-γ (top panels) or TNF (bottom panels) expression by NK cells (viable CD3–CD56+ cells). Symbols represent individual donors, and grey columns indicate mean. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns = not significant (Repeated measures one-way ANOVA with Tukey correction (A) or Friedman test with Dunn’s correction (B)). Data are from nine donors (A) or seven donors (B).