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VPS38/UVRAG, ATG14 and ATG6/Beclin1 are transcriptionally regulated in the oocytes of Rhodnius prolixus.

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posted on 07.09.2021, 17:40 authored by Priscila H. Vieira, Claudia F. Benjamim, Georgia Atella, Isabela Ramos

Oocytes dissected from silenced females were tested for the expression levels of the other class III PI3K components, and for the control genes ATG8/LC3, ATG1/ULK1, EF1 and PERK (non-related to the class III PI3K complexes). A. Expression levels of different genes in the ovaries of females silenced for VPS38/UVRAG (dsVPS38). B. Expression levels of different genes in the ovaries of females silenced for ATG14 (dsATG14). C. Expression levels of different genes in the ovaries of females silenced for ATG6/Beclin1 (dsATG6/Beclin1). Graphs show mean ± SEM. (n = 8) **p<0.01,***p<0.001. One Way ANOVA. D. Model for the transcriptional regulations between ATG6/Beclin1, VPS38/UVRAG and ATG14.

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