pcbi.1008750.g001.tif (3.71 MB)
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VDAC embedded in a lipid bilayer.

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posted on 12.02.2021, 18:41 by Jordane Preto, Isabelle Krimm

The structure of the murine VDAC1 (mVDAC1) solved by X-ray crystallography was used (PDB ID: 3EMN [9]). The inset shows a closer view of the N-terminal region with the 310-helix involving Y7, A8 and D9, depicted in dark blue, and the standard helix (K12 to T19) in fuchsia. Chloride (in blue-green) and potassium ions (in pink) are also shown at a 150-mM KCl concentration for illustrative purposes. The MOM as well as expected cytoplasm and IMS sides are also indicated.