Two-dimensional NMR analysis of K2 polysaccharide extracted from E. coli expressing the decoupled K2 gene cluster.
figure
posted on 2023-05-05, 17:38 authored by Paeton L. Wantuch, Cory J. Knoot, Lloyd S. Robinson, Evgeny Vinogradov, Nichollas E. Scott, Christian M. Harding, David A. Rosen(A) 1H-13C HSQC spectrum of the extracted K2 polysaccharide. Orange hash indicates cut water peak. (B) NMR data for the K2 polysaccharide (D2O, 25°C, 600 MHz). The data show the expected peaks based on the known K2 structure [8].
(TIF)
History
Usage metrics
Categories
Keywords
using murine modelstwo circulating pathotypesserum bactericidal assays>: capsular polysaccharidetwo bioconjugate vaccinesbased vaccines mayk2 capsular serotypestrains exhibited decreasedantibiotic resistance profilesklebsiella pneumoniae k2 vaccine outperformedcapsule blocks o1antigen antibody bindingantibody bindingantibiotic resistancepneumoniae antigen vaccinesrecognize k2antibiotic susceptiblekp k vaccine candidatesremains unclearpractical advantageso1 vaccineo1 strainskp )investigated whetherincreased rateshypervirulent k2gained tractionencapsulated strainseffective immunotherapiesdata suggestcapsule blockingantigens included
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC