Treatment with enalapril and not diltiazem ameliorated progression of chronic kidney disease in rats, and normalized renal AT1 receptor expression as measured with PET imaging - Fig 2
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Body weight data obtained weekly over 10 weeks (A), terminal left kidney weight for sham (N = 8), Nx (N = 8), NxE (N = 6) and NxD (N = 8) (B) and heart weight for sham (N = 8), Nx (N = 9), NxE (N = 9) and NxD (N = 8) (C) normalized to body weight at 18–20 weeks post-surgery. Data are presented as mean±SD. * p<0.05 vs sham, $ p<0.05 vs Nx, # p<0.05 vs NxE (p<0.05).