Total CD34+KDR+ cells across pregnancy and postpartum in control, type 1 and type 2 diabetic women.
(A) Absolute numbers (per 105 mononuclear cells) of circulating CD45dimCD34+SSlowKDR+ (CD34+KDR+) cells across pregnancy and postpartum from control (i), type 1 (ii) and type 2 (iii) diabetic women. In control women, CD34+KDR+ cells were elevated in 3rd trimester and significantly higher compared to 2nd trimester (p = 0.013; i). Such fluctuation was not observed in type 1 and type 2 diabetic women (i, ii). (B) Comparisons between control (green) and type 1 (red) (i) and type 2 diabetes (black) (ii) at 1st trimester demonstrated that type 1 (p = 0.033), but not type 2 diabetic women (p = 0.090) had significantly more CD34+KDR+ CACs than control women. No differences were found when comparing control and diabetic (type 1 and type 2) women at 2nd, 3rd trimester and postpartum stages. Data in A were compared using Kruskal-Wallis test; B using Mann-Whitney test, considering p<0.05. Data in Bi and Bii were shown as a rank score graphic.